NANBV diagnostics: polynucleotides useful for screening for hepatitis C virus

US5714596A · kind A · utility

Assignee

• Chiron Corporation · US

Inventors

• Michael Houghton · Berkeley, US
• Qui-Lim Choo · Corona, US
• George Kuo · San Francisco, US
• Amy J. Weiner · Berkeley, US
• Jang Han · Lafayette, US
• Michael S. Urdea · Alamo, US
• Bruce D. Irvine · Glendora, US
• Janice A. Kolberg · Hercules, US

Key dates

• Filing date: Mar 31, 1993
• Grant date: Feb 3, 1998
• Expiry date: Mar 31, 2013

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T436/143333
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A new virus, Hepatitis C virus (HCV), which has proven to be the major etiologic agent of blood-borne NANBH, was discovered by Applicant. Reagents for isolating, amplifying, and detecting HCV polynucleotides are provided. These reagents are oligomers comprised of polynucleotide sequences which are capable of forming hybrid structures with HCV target polynucleotide sequences.