Patent · US Expired

Tricyclic inhibitors of the vitronectin receptor

US5716951A · kind A · utility

3Cited by
3References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 8, 1995
Grant dateFeb 10, 1998
Priority date
Expiry dateMay 8, 2015

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P7/02
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A tricylic benzodiazepine derivative that acts as a nonpeptidyl platelet aggregation inhibitor is provided. This inhibitor potently inhibits fibrinogen binding to the GPII.sub.b III.sub.a receptor and is provided in therapeutic compositions for the treatment of diseases for which blocking platelet aggregation is indicated. These nonpeptidyl inhibitors are provided in combination with thrombolytics and anticoagulants.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.