Peptide nucleic acids having amino acid side chains
US5719262A · kind A · utility
481Cited by
3References
11Claims
0Family size
Inventors
Key dates
| Filing date | Jul 24, 1996 |
| Grant date | Feb 17, 1998 |
| Priority date | — |
| Expiry date | Jul 24, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6869
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A novel class of compounds, known as peptide nucleic acids, bind complementary DNA and RNA strands more strongly than the corresponding DNA or RNA strands, and exhibit increased sequence specificity and solubility. The peptide nucleic acids comprise ligands selected from a group consisting of naturally-occurring nucleobases and non-naturally-occurring nucleobases attached to a polyamide backbone, and contain alkylamine side chains.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.