Inventor · Wayland, MA, US

Michael Egholm

42Patents
23h-index
43Co-inventors
81Inventor score

Filing activity: Apr 26, 1993 → Aug 10, 2009

Most-cited inventions

PatentTitleAreaCited byStatus
US5539082A Peptide nucleic acids Chemistry; Metallurgy 724 Expired
US5714331A Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility Emerging Cross-Sectional Technologies 502 Expired
US5719262A Peptide nucleic acids having amino acid side chains Chemistry; Metallurgy 481 Expired
US5773571A Peptide nucleic acids Chemistry; Metallurgy 142 Expired
US5891625A Use of nucleic acid analogues in the inhibition of nucleic acid amplification Chemistry; Metallurgy 115 Expired
US5736336A Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility Emerging Cross-Sectional Technologies 109 Expired
US5786461A Peptide nucleic acids having amino acid side chains Chemistry; Metallurgy 93 Expired
US6297016A Template-dependent ligation with PNA-DNA chimeric probes Chemistry; Metallurgy 84 Expired
US7223833B1 Peptide nucleic acid conjugates Chemistry; Metallurgy 76 Expired
US6316230A Polymerase extension at 3' terminus of PNA-DNA chimera Chemistry; Metallurgy 75 Expired
US6451588B1 Multipartite high-affinity nucleic acid probes Chemistry; Metallurgy 73 Expired
US5766855A Peptide nucleic acids having enhanced binding affinity and sequence specificity Emerging Cross-Sectional Technologies 64 Expired
US5986053A Peptide nucleic acids complexes of two peptide nucleic acid strands and one nucleic acid strand Chemistry; Metallurgy 60 Expired
US6395474B1 Peptide nucleic acids Human Necessities 57 Expired
US5972610A Use of nucleic acid analogues in the inhibition of nucleic acid amplification Chemistry; Metallurgy 51 Expired
US7601499B2 Paired end sequencing Chemistry; Metallurgy 50 Active
US6107470A Histidine-containing peptide nucleic acids Chemistry; Metallurgy 47 Expired
US5837459A Nucleic acid analogue induced transcription of double stranded DNA Chemistry; Metallurgy 42 Expired
US5641625A Cleaving double-stranded DNA with peptide nucleic acids Chemistry; Metallurgy 35 Expired
US6228982A Double-stranded peptide nucleic acids Chemistry; Metallurgy 35 Expired
US6357163B1 Use of nucleic acid analogues in diagnostics and analytical procedures Human Necessities 32 Expired
US7553619B2 Detection method using dissociated rolling circle amplification Chemistry; Metallurgy 27 Expired
US6613873B1 Peptide nucleic acids having 2,6-diaminopurine nucleobases Human Necessities 26 Expired
US6432642B1 Binary probe and clamp composition and methods for a target hybridization detection Chemistry; Metallurgy 23 Expired
US6441130B1 Linked peptide nucleic acids Chemistry; Metallurgy 20 Expired

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.