Peptide library and screening systems
US5723286A · kind A · utility
93Cited by
4References
45Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 20, 1990 |
| Grant date | Mar 3, 1998 |
| Priority date | — |
| Expiry date | Jun 20, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Peptides which bind to selected receptor molecules are identified by screening libraries which encode a random or controlled collection of amino acids. Peptides encoded by the libraries are expressed as fusion proteins of bacteriophage coat proteins, and bacteriophage particles are then screened against the receptors of interest. Peptides having a wide variety of uses, such as therapeutic or diagnostic reagents, may thus be identified without any prior information on the structure of the expected ligand or receptor molecule.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.