Method for diagnosing chronic hepatitis B virus infection

US5726011A · kind A · utility

Assignees

• Virginia Commonwealth University · US
• THE SCRIPPS RESEARCH INSTITUTE · US
• Max-Planck-Gesellschaft · DE

Inventors

• David R. Milich · San Diego, US
• Toshiyuki Maruyama · Tokyo, JP
• Florian Schodel · Cumberland, US
• Darrel Peterson · Midlothian, US

Key dates

• Filing date: Mar 31, 1994
• Grant date: Mar 10, 1998
• Expiry date: Mar 31, 2014

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S436/82
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Human antibodies that bind to woodchuck hepatitis virus core antigen are elevated in chronic hepatitis B patients in comparison to acute hepatitis B patients. Immunoassays for detection of the level of anti-WHV core antigen antibodies is used to distinguish chronic from acute hepatitis B patients.