Human mutant tissue factor compositions useful as tissue factor antagonists
US5726147A · kind A · utility
24Cited by
1References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 18, 1995 |
| Grant date | Mar 10, 1998 |
| Priority date | — |
| Expiry date | Apr 18, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention describes a mutant human tissue factor protein which binds functional Factor VII/VIIa but is substantially free of functional procoagulant cofactor activity, and compositions containing the mutant protein. Also disclosed are methods for using the mutant human tissue factor proteins, and recombinant DNA vectors for expressing the protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.