Tetralin compounds with improved MDR activity
US5726184A · kind A · utility
12Cited by
1References
20Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | May 19, 1995 |
| Grant date | Mar 10, 1998 |
| Priority date | — |
| Expiry date | May 19, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to compounds that can maintain, increase, or restore sensitivity of cells to therapeutic or prophylactic agents. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well-suited for treatment of multi-drug resistant cells, for prevention of the development of multi-drug resistance, and for use in multi-drug resistant cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.