Peptide library and screening method
US5733731A · kind A · utility
114Cited by
11References
27Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 26, 1995 |
| Grant date | Mar 31, 1998 |
| Priority date | — |
| Expiry date | Oct 26, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6811
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A random peptide library constructed by transforming host cells with a collection of recombinant vectors that encode a fusion protein comprised of a DNA binding protein and a random peptide and also encode a binding site for the DNA binding protein can be used to screen for novel ligands. The screening method results in the formation of a complex comprising the fusion protein bound to a receptor through the random peptide ligand and to the recombinant DNA vector through the DNA binding protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.