Combinatorial oligomer immunoabsorbant screening assay for transcription factors and other biomolecule binding
US5747253A · kind A · utility
11Cited by
4References
68Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 8, 1995 |
| Grant date | May 5, 1998 |
| Priority date | — |
| Expiry date | Feb 8, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6811
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods useful for the determination of oligomers which have specific activity for a transcription factor or other target molecule from a pool of primarily randomly assembled subunits are provided. The disclosed methods involve repeated syntheses of increasingly simplified sets of oligomers coupled with novel selection procedures for determining oligomers having the highest activity. Freedom from the use of enzymes allows the application of these methods to any molecules which can be oligomerized in a controlled fashion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.