Heterodimeric receptor libraries using phagemids
US5759817A · kind A · utility
54Cited by
3References
26Claims
0Family size
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Key dates
| Filing date | Oct 12, 1994 |
| Grant date | Jun 2, 1998 |
| Priority date | — |
| Expiry date | Oct 12, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Filamentous phage comprising a matrix of cpVIII proteins encapsulating a genome encoding first and second polypeptides of an antogenously assembling receptor, such as an antibody, and a receptor comprised of the first and second polypeptides surface-integrated into the matrix via a cpVIII membrane anchor domain fused to at least one of the polypeptides with a mutagenized CDR3 region.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.