Process for the synthesis of 2'-O-substituted pyrimidines
US5760202A · kind A · utility
30Cited by
4References
8Claims
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Key dates
| Filing date | Jun 7, 1995 |
| Grant date | Jun 2, 1998 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/582
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Improved processes for the synthesis of 2'-O-substituted pyrimidine nucleosides are provided. The processes feature alkylation of a 2,2'-anhydropyrimidine nucleoside or a 2S,2'-anhydropyrimidine nucleoside with a weak nucleophile in the presence of a Lewis acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.