Systematic evolution of ligands by exponential enrichment: tissue SELEX
US5763566A · kind A · utility
34Cited by
1References
5Claims
0Family size
Assignee
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Key dates
| Filing date | May 3, 1995 |
| Grant date | Jun 9, 1998 |
| Priority date | — |
| Expiry date | May 3, 2015 |
Classification
- Technology area (CPC F)Mechanical Engineering; Lighting; Heating
- CPC primaryF02B2075/027
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention discloses high-affinity oligonucleotide ligands to complex tissue targets, specifically nucleic acid ligands having the ability to bind to complex tissue targets, and the methods for obtaining such ligands. Tissue targets comprise cells, subcellular components, aggregates or cells, collections of cells, and higher ordered structures. Specifically, nucleic acid ligands to red blood cells ghosts, glioblastomas, and lymphomas are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.