Separation of polar compounds by affinity countercurrent chromatography
US5770083A · kind A · utility
8Cited by
15References
9Claims
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Key dates
| Filing date | Aug 14, 1995 |
| Grant date | Jun 23, 1998 |
| Priority date | — |
| Expiry date | Aug 14, 2015 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N30/42
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Separations of very hydrophilic organic compounds has now been achieved using countercurrent chromatography in which a ligand for the analytes of interest is used to enhance the partitioning of the polar species into the organic layer of an aqueous/organic solvent mixture. The compounds are separated according to their affinity for the ligand in the stationary organic phase. This method of affinity countercurrent chromatography can also be conducted in a pH-zone refining mode.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.