Isolation characterization, and use of the human beta subunit of the high affinity receptor for immunoglobulin E
US5770396A · kind A · utility
7Cited by
6References
20Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 16, 1992 |
| Grant date | Jun 23, 1998 |
| Priority date | — |
| Expiry date | Apr 16, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to nucleic acid sequences, encoding amino acid sequences of the .alpha., .beta., and .gamma. subunits of the high affinity receptor for immunoglobulin E, and for amino acid sequences of the subunits. The invention further relates to a method of producing the receptor by expressing cDNA for its .alpha., .beta., and .gamma. subunits in a host cell simultaneously. Aspects of the invention are methods and compositions to inhibit the function of the human beta subunit, thereby treating or preventing allergic reactions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.