Covalent lock for self-assembled oligonucleotide constructs
US5780613A · kind A · utility
131Cited by
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10Claims
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Key dates
| Filing date | Aug 1, 1995 |
| Grant date | Jul 14, 1998 |
| Priority date | — |
| Expiry date | Aug 1, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H21/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method of autoligating self-assembled oligonucleotide blocks is disclosed. The method includes the step of displacing a 5' displaceable group by a 3' thiophosphoryl group to form an --OP(O)(O.sup.-)S-- internucleoside linkage.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.