Protecting group for synthesizing oligonucleotide analogs
US5783690A · kind A · utility
11Cited by
40References
9Claims
0Family size
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Key dates
| Filing date | Sep 18, 1997 |
| Grant date | Jul 21, 1998 |
| Priority date | — |
| Expiry date | Sep 18, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A 2-N-amidoethyl protected nucleoside analog phosphoramidite of formula (1): ##STR1## is useful in the synthesis of a wide variety of oligonucleotide analogs. Coupling yields with phosphoramidite (1) in solution or solid phase oligonucleotide analog synthesis are high and the 2-N-amidoethyl protecting group can be removed easily under standard conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.