Peptide nucleic acids having amino acid side chains
US5786461A · kind A · utility
93Cited by
3References
9Claims
0Family size
Inventors
Key dates
| Filing date | May 1, 1997 |
| Grant date | Jul 28, 1998 |
| Priority date | — |
| Expiry date | May 1, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6869
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A novel class of compounds, known as peptide nucleic acids, bind complementary DNA and RNA strands more strongly than the corresponding DNA or RNA strands, and exhibit increased sequence specificity and solubility. The peptide nucleic acids comprise ligands selected from a group consisting of naturally-occurring nucleobases and non-naturally-occurring nucleobases attached to a polyamide backbone, and contain alkylamine side chains.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.