Patent · US Expired

Steroid secreting human adrenocortical carcinoma cell lines

US5792657A · kind A · utility

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Assignee

Inventors

Key dates

Filing dateJun 7, 1995
Grant dateAug 11, 1998
Priority date
Expiry dateJun 7, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N5/0693
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Continuous cell lines have been established from adrenocortical corcinomas. The cell lines are maintained in fully defined serum-free, steroid-free mediums. The cells of the invention, as exemplified by NCI-H295 cells, express all of the major pathways of steroid-ogenesis, including formation of corticosteroids, mineralocorticoids and androgens.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.