Analogs for specific oligosaccharide-protein interactions and uses therefor
US5795860A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 28, 1994 |
| Grant date | Aug 18, 1998 |
| Priority date | — |
| Expiry date | Feb 28, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are (1) methods for identifying natural and synthetic sequences having binding specificity for glycan-binding proteins, including proteins that act as effectors of biological activity, (2) compositions and methods of producing protein-specific glycosaminoglycan sequence and ligand antagonists capable of modulating the effector function of these ligands, and therapeutic compositions comprising these antagonists; and 3) compositions and methods for producing protein-specific glycosaminoglycan sequence analogs useful as agonists, and therapeutic compositions comprising these agonists.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.