Patent · US Expired

Water soluble adenosine kinase inhibitors

US5795977A · kind A · utility

90Cited by
2References
21Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 7, 1996
Grant dateAug 18, 1998
Priority date
Expiry dateJun 7, 2016

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H19/16
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

This invention relates to adenosine kinase inhibitors and to nucleoside analogs, specifically to water soluble, aryl substituted 4-amino pyrrolo2,3-d! pyrimidine and pyrazolo3,4-d! pyrimidine nucleoside analogs having activity as adenosine kinase inhibitors The invention also relates to the preparation and use of these adenosine kinase inhibitors in the treatment of cardiovascular, and cerebrovascular diseases, inflammation and other diseases which can be regulated by increasing the local concentration of adenosine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.