Monoclonal antibodies
US5798213A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 21, 1996 |
| Grant date | Aug 25, 1998 |
| Priority date | — |
| Expiry date | Aug 21, 2016 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2474/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides monoclonal antibodies against peptides having an amino acid sequence described in Sequence No. 1 or No. 2, the peptides being found in human thymidine phosphorylase and human platelet-derived endothelial cell growth factor. The Invention also provides an immunoassay for human thymidine phosphorylase and/or human platelet-derived endothelial cell growth factor using the monoclonal antibodies. The monoclonal antibodies of the invention recognize human thymidine phosphorylase and human platelet-derived endothelial cell growth factor, and thus are useful in the diagnosis and treatment of various tumors and their metastasis and diseases accompanying abnormal angiogenesis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.