Deprotection of RNA with alkylamine
US5804683A · kind A · utility
69Cited by
6References
1Claims
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Key dates
| Filing date | May 5, 1995 |
| Grant date | Sep 8, 1998 |
| Priority date | — |
| Expiry date | May 5, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for the deprotection of RNA comprising reacting an alkylamine or ammonium hydroxide/alkylamine mixture with the RNA at 60-70 degrees Centigrade for 5 to 15 minutes in order to remove any exocyclic protecting groups, wherein said alkylamine is selected from the group consisting of ethylamine, propylamine, and butylamine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.