Aptamer analogs specific for biomolecules
US5840867A · kind A · utility
129Cited by
4References
4Claims
0Family size
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Key dates
| Filing date | May 3, 1994 |
| Grant date | Nov 24, 1998 |
| Priority date | — |
| Expiry date | May 3, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6811
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Oligonucleotide sequences that mediate specific binding to selected target molecules and contain modified base, sugars, or sugar linkages are disclosed. Single-stranded DNA oligomers are obtained that bind to a series of biomolecules that differ in both size and composition. The range of target molecules that may be bound permits generation of binding oligomers that are specific for binding to nearly any biomolecule that is composed of amino acids, lipids and/or carbohydrates. The binding oligomers are useful for therapeutic, diagnostic and manufacturing purposes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.