Systematic polypeptide evolution by reverse translation
US5843701A · kind A · utility
89Cited by
1References
40Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 31, 1992 |
| Grant date | Dec 1, 1998 |
| Priority date | — |
| Expiry date | Jan 31, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6806
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method for preparing polypeptide ligands of target molecules wherein candidate mixtures comprised of ribosome complexes or mRNA.multidot.polypeptide copolymers are partitioned relative to their affinity to the target and amplified to create a new candidate mixture enriched in ribosome complexes or mRNA.multidot.polypeptide copolymers with an affinity to the target.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.