Redirection of cellular immunity by receptor chimeras
US5843728A · kind A · utility
79Cited by
8References
55Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 5, 1995 |
| Grant date | Dec 1, 1998 |
| Priority date | — |
| Expiry date | Apr 5, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a method of directing a cellular response in a mammal by expressing in a cell of the mammal a chimeric receptor which causes the cells to specifically recognize and destroy an infective agent, a cell infected with an infective agent, a tumor or cancerous cell, or an autoimmune-generated cell. Also disclosed are cells which express the chimeric receptors and DNA encoding the chimeric receptors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.