Inventor · Boston, MA, US

Brian Seed

77Patents
27h-index
71Co-inventors
91Inventor score

Filing activity: Oct 12, 1979 → Mar 13, 2020

Most-cited inventions

PatentTitleAreaCited byStatus
US7049136B2 Redirection of cellular immunity by receptor chimeras Chemistry; Metallurgy 120 Expired
US5506126A Rapid immunoselection cloning method Chemistry; Metallurgy 120 Expired
US6114148A High level expression of proteins Chemistry; Metallurgy 119 Expired
US5795737A High level expression of proteins Chemistry; Metallurgy 102 Expired
US5851828A Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells Chemistry; Metallurgy 92 Expired
US5786464A Overexpression of mammalian and viral proteins Chemistry; Metallurgy 92 Expired
US6753162B1 Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells Chemistry; Metallurgy 91 Expired
US7320787B2 Redirection of cellular immunity by protein tyrosine kinase chimeras Chemistry; Metallurgy 83 Expired
US6284240A Targeted cytolysis of HIV-infected cells by chimeric CD4 receptor-bearing cells Chemistry; Metallurgy 83 Expired
US5843728A Redirection of cellular immunity by receptor chimeras Chemistry; Metallurgy 79 Expired
US5081034A Cloned genes which encode ELAM-1 Chemistry; Metallurgy 78 Expired
US6004811A Redirection of cellular immunity by protein tyrosine kinase chimeras Chemistry; Metallurgy 70 Expired
US6410014B1 Redirection of cellular immunity by protein-tyrosine kinase chimeras Chemistry; Metallurgy 67 Expired
US6392013B1 Redirection of cellular immunity by protein tyrosine kinase chimeras Chemistry; Metallurgy 67 Expired
US5858983A Inhibition of cell adhesion protein-carbohydrate interactions Emerging Cross-Sectional Technologies 66 Expired
US5912170A Redirection of cellular immunity by protein-tyrosine kinase chimeras Chemistry; Metallurgy 66 Expired
US5227293A Fusion proteins, their preparation and use Chemistry; Metallurgy 64 Expired
US5358857A Method of preparing fusion proteins Chemistry; Metallurgy 59 Expired
US5925657A Use of PPAR.gamma. agonists for inhibition of inflammatory cytokine production Human Necessities 55 Expired
US5849898A CD40 coding sequences Chemistry; Metallurgy 55 Expired
US5723583A Antibody containing sialyl lewis X determinants Emerging Cross-Sectional Technologies 53 Expired
US5858752A Fucosyltransferase genes and uses thereof Chemistry; Metallurgy 52 Expired
US6117656A Cloned genes encoding IG-CD4 fusion proteins and the use thereof Chemistry; Metallurgy 41 Expired
US6004781A Nucleic acid encoding Ig-CD4 fusion proteins Chemistry; Metallurgy 36 Expired
US8993295B2 Methods, compositions, and kits for the selective activation of protoxins through combinatorial targeting Emerging Cross-Sectional Technologies 32 Active

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.