Patent · US Expired

Peptidomimetic inhibitors of cathepsin D and plasmepsins I and II

US5849691A · kind A · utility

14Cited by
2References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 20, 1996
Grant dateDec 15, 1998
Priority date
Expiry dateFeb 20, 2016

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to the design and synthesis of linear and cyclic inhibitors of cathepsin D and plasmepsins I and II. The present invention also relates to the uses of these inhibitors for inhibiting invasion and metastasis of cancerous cells. The present invention further relates to the use of cathepsin D and plasmepsin I and II inhibitors for the prevention and treatment of Alzheimer's disease and malaria.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.