Rapid detection of antibiotic resistance in mycobacterium tuberculosis
US5851763A · kind A · utility
16Cited by
2References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 12, 1994 |
| Grant date | Dec 22, 1998 |
| Priority date | — |
| Expiry date | Oct 12, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A process for the detection of resistance to an antibiotic in a mycobacterium comprises detecting a mutation in a gene selected from the group consisting of the katG gene or fragment thereof, the rpoB gene or fragment thereof, and the rpsI gene or fragment thereof. The process is useful for detecting in vitro the presence of nucleic acids of a Mycobacterium tuberculosis resistant to isoniazid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.