Hepatitis C virus isolate polypeptides

US5856437A · kind A · utility

Assignees

• Chiron Corporation · US
• The Director General of the National Institute of Health of Japan · JP

Inventors

• Tatsuo Miyamura · Tokyo, JP
• Izumi Saito · Tokyo, JP
• Michael Houghton · Berkeley, US
• Amy J. Weiner · Berkeley, US
• Jang Han · Lafayette, US
• Janice A. Kolberg · Hercules, US
• Tai-An Cha · San Ramon, US
• Bruce D. Irvine · Glendora, US

Key dates

• Filing date: Nov 3, 1994
• Grant date: Jan 5, 1999
• Expiry date: Nov 3, 2014

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/826
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Two new isolates of the Hepatitis C virus (HCV), J1 and J7, are disclosed. These new isolates comprise nucleotide and amino acid sequences which are distinct from the prototype HCV isolate, HCV1. Thus, J1 and J7 provide new polynucleotides and polypeptides for use, inter alia, in diagnostics, recombinant protein production and vaccine development.