Liposomal formulations of mitoxantrone
US5858397A · kind A · utility
33Cited by
6References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 11, 1995 |
| Grant date | Jan 12, 1999 |
| Priority date | — |
| Expiry date | Oct 11, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1271
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions and methods which are useful for the treatment of solid tumors in a host and which are also useful for increasing the therapeutic index of mitoxantrone in a host. The pharmaceutical compositions are liposomal formulations of mitoxantrone in which the liposomes comprise a mixture of cholesterol and a diacylphosphatidylcholine, preferably 1,2-sn-dimyristoyl-phosphatidylcholine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.