Patent · US Expired

Piperazine based cytofectins

US5861397A · kind A · utility

42Cited by
9References
35Claims
0Family size

Assignee

Inventor

Key dates

Filing dateOct 3, 1996
Grant dateJan 19, 1999
Priority date
Expiry dateOct 3, 2016

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S424/812
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to piperazine based amphilic cationic lipids useful for gene therapy, transfection, and introducing immunogenic compounds for the purpose of vaccination. The disclosed compounds have lipophilic moieties linked to the ring nitrogens. In addition, at least one of the ring nitrogens is quatranized and linked to a hydrocarbon having at least one heteroatom.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.