Arylglycinamide derivatives and pharmaceutical compositions containing these compounds

US5861509A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Gerd Schnorrenberg · Ingelheim am Rhein, DE
• Horst Dollinger · Schemmerhofen, DE
• Franz Esser · Ingelheim am Rhein, DE
• Hans Briem · Bremen, DE
• Birgit Jung · Laupheim, DE
• Georg Speck · Ingelheim am Rhein, DE

Key dates

• Filing date: Oct 9, 1997
• Grant date: Jan 19, 1999
• Expiry date: Oct 9, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to new arylglycinamide derivatives of general formula I ##STR1## and the pharmaceutically acceptable salts thereof, wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and Ar have the meanings given in the specification, and the preparation and use thereof. The new compounds are valuable neurokin (tachykinin) antagonists.