In vivo imaging and oxymetry by pulsed radiofrequency paramagnetic resonance

US5865746A · kind A · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Ramachandran Murugesan · Rockville, US
• Murali K. Cherukuri · North Potomac, US
• James B. Mitchell · Damascus, US
• Sankaran Subramanian · Kothagudem, IN
• Rolf G. Tschudin · Kensington, US

Key dates

• Filing date: Jul 29, 1997
• Grant date: Feb 2, 1999
• Expiry date: Jul 29, 2017

Classification

• Technology area (CPC G): Physics
• CPC primary: G01R33/3621
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A system for performing pulsed RF FT EPR spectroscopy and imaging includes an ultra-fast excitation subsystem and an ultra-fast data acquisition subsystem. Additionally, method for measuring and imaging in vivo oxygen and free radicals or for performing RF FT EPR spectroscopy utilizes short RF excitations pulses and ultra-fast sampling, digitizing, and summing steps.