Antigen-carrying microparticles and their use in the indication of humoral or cellular responses
US5871747A · kind A · utility
116Cited by
2References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 28, 1995 |
| Grant date | Feb 16, 1999 |
| Priority date | — |
| Expiry date | Apr 28, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/918
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns the use, in the induction of an immune response, of a synthetic microparticle polymer carrying on the surface one or more covalently bonded proteins capable of carrying one or more epitopes, the densities of the protein(s) on the surface of the microparticles, and their molecular weights, being adjusted so as to direct the immune response to the induction of a humoral and cellular response or to the induction of a largely cellular response. Said microparticles have an average diameter of approximately 0.25 to 1.5 .mu.m.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.