Patent · US Expired

Method for the production of ligands capable of facilitating aminoacyl-RNA synthesis

US5871924A · kind A · utility

5Cited by
1References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 27, 1997
Grant dateFeb 16, 1999
Priority date
Expiry dateJan 27, 2017

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/6811
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

The instant invention provides a method for identifying and preparing nucleic acid ligands capable of facilitating aminoacyl-RNA synthesis. The nucleic acid ligands are identified and produced by exposure of candidate nucleic sequences to a reactant under conditions conducive to reaction, wherein nucleic acid sequences having facilitative activity are able to facilitate or enhance a reaction between the reactant molecule and nucleic acid sequence. Included in the invention are specific RNA ligands capable of facilitating aminoacyl-RNA synthesis identified by the SELEX method.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.