Conformationally constrained diacylglycerol analogues

US5874464A · kind A · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Victor E. Marquez · Gaithersburg, US
• Jeewoo Lee · Ansan-si, KR
• Rajiv Sharma · Mumbai, IN
• Shaomeng Wang · Saline, US
• George W. A. Milne · Bethesda, US
• Marc C. Nicklaus · Elkridge, US
• Peter M. Blumberg · Frederick, US
• Nancy E. Lewin · Rockville, US

Key dates

• Filing date: Jan 13, 1995
• Grant date: Feb 23, 1999
• Expiry date: Jan 13, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D307/58
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Conformationally constrained diacylglycerol analogues, pharmaceutical compositions comprising such analogues, and methods of using such analogues as agonists and antagonists of protein kinase C.