Nucleic acid ligand inhibitors to DNA polymerases
US5874557A · kind A · utility
18Cited by
13References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 7, 1995 |
| Grant date | Feb 23, 1999 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/9125
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
High-affinity oligonucleotide ligands to the thermostable Taq polymerase and Tth polymerase are disclosed. Specifically disclosed are DNA ligands having the ability to bind to the Taq and Tth polymerases and the methods for obtaining such ligands. The ligands are capable of inhibiting polymerases at ambient temperatures.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.