Nucleotide analogs
US5886179A · kind A · utility
35Cited by
15References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 29, 1995 |
| Grant date | Mar 23, 1999 |
| Priority date | — |
| Expiry date | Dec 29, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/20
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Nucleotide phosphonate esters characterized by the presence of an ester linked group which is bonded to the phosphorus atom of phosphonate nucleotide analogs are disclosed. The analogs comprise an ester bond that is hydrolyzed in vivo to yield a corresponding phosphonate nucleotide analog. Methods and intermediates for their synthesis and use are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.