Patent · US Expired

TNF deletion muteins

US5889156A · kind A · utility

10Cited by
30References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 24, 1995
Grant dateMar 30, 1999
Priority date
Expiry dateMay 24, 2015

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S930/144
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A virion expression system for a desired protein packaged in an envelope derived from a retrovirus useful in administering proteins which cross cell membranes in order to serve their function. Preferred virions are those that carry an RNA sequence that encodes cytokines or lymphokines, and includes IL-2, multiple drug resistance protein, and TNF.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.