Affinity selection of ligands by mass spectroscopy
US5891742A · kind A · utility
10Cited by
4References
4Claims
0Family size
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Key dates
| Filing date | Jan 19, 1995 |
| Grant date | Apr 6, 1999 |
| Priority date | — |
| Expiry date | Jan 19, 2015 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Compounds are quickly selected from a combinatorial library by contacting the library with a target (e.g., receptor), separating non-binding compounds from compound-target complexes, and analyzing the complexes or eluted compound by mass spectroscopy. SAR information is obtained by performing this selection at two or more different ratios of compound to target.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.