N-benzylazolium derivatives
US5900486A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 9, 1997 |
| Grant date | May 4, 1999 |
| Priority date | — |
| Expiry date | Sep 9, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D249/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
N-Benzylazolium derivatives of the general formula (I), ##STR1## wherein Q is the remainder of an azole compound of the formula II ##STR2## possessing antifungal activity; Z is nitrogen or methine; PA1 R.sup.1 and R.sup.2 are each independently a hydrogen atom or a group --OY in which Y is a group easily hydrolyzable under physiological condition!; PA1 R.sup.3 and R.sup.4 are each independently a hydrogen or halogen atom, lower alkyl, lower alkoxy, lower alkylthio, (lower alkylcarbonyl)thiomethyl, carboxy or methoxycarbonyl; and PA1 X.sup.- is a pharmaceutically acceptable anion, as well as salts, hydrates or solvates of the compounds of the general formula (I) have antifungal properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.