6-triazolyl3-(trifluoromethyl)phenyl!methyl!-2-quinolines and -quinolinethiones
US5922734A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 16, 1997 |
| Grant date | Jul 13, 1999 |
| Priority date | — |
| Expiry date | Jun 16, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D233/56
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention is concerned with the compounds of formula ##STR1## the pharmaceutically acceptable acid addition salts and the stereochemically isomeric forms thereof, PA1 wherein: R.sup.1 is hydrogen, amino or C.sub.1-4 alkyl; R.sup.2 is hydrogen, halo or C.sub.1-4 alkyl; R.sup.3 is hydrogen, halo or C.sub.1-4 alkyl; Y is 0 or S, and --X.sup.1 .dbd.X.sup.2 --is a bivalent radical having the formula --N.dbd.CH--(a-1) or --CH.dbd.N--(a-2); compositions containing the same, and processes of preparing these compounds. It further relates to their use as a medicine, in particular their use as a medicine to treat keratinization disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.