Immunotherapeutic agents
US5929117A · kind A · utility
154Cited by
1References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 11, 1997 |
| Grant date | Jul 27, 1999 |
| Priority date | — |
| Expiry date | Aug 11, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Cyano and carboxy derivatives of substituted styrenes are inhibitors of tumor necrosis factor .alpha., nuclear factor .kappa.B, and phosphodiesterase and can be used to combat cachexia, endotoxic shock, retrovirus replication, asthma, and inflammatory conditions. A typical embodiment is 3,3-bis-(3,4-dimethoxyphenyl)acrylonitrile.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.