Inventor · Northbrook, IL, US

George W. Muller

174Patents
37h-index
42Co-inventors
90Inventor score

Filing activity: Oct 2, 1987 → Sep 2, 2021

Most-cited inventions

PatentTitleAreaCited byStatus
US5635517A Method of reducing TNF.alpha. levels with amino substituted 2-(2,6-dioxopiperidin-3-yl)-1-oxo-and 1,3-dioxoisoindolines Emerging Cross-Sectional Technologies 275 Expired
US5698579A Cyclic amides Chemistry; Metallurgy 172 Expired
US5877200A Cyclic amides Chemistry; Metallurgy 170 Expired
US6281230A Isoindolines, method of use, and pharmaceutical compositions Human Necessities 161 Expired
US6316471A Isoindolines, method of use, and pharmaceutical compositions Human Necessities 159 Expired
US5929117A Immunotherapeutic agents Chemistry; Metallurgy 154 Expired
US5798368A Tetrasubstituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines and method of reducing TNF.alpha. levels Chemistry; Metallurgy 153 Expired
US6458810B1 Pharmaceutically active isoindoline derivatives Chemistry; Metallurgy 150 Expired
US6476052B1 Isoindolines, method of use, and pharmaceutical compositions Human Necessities 149 Expired
US6335349B1 Substituted 2(2,6-dioxopiperidin-3-yl)isoindolines Human Necessities 142 Expired
US5955476A Substituted 2-(2,6-dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing inflammatory cytokine levels Human Necessities 142 Expired
US6020358A Substituted phenethylsulfones and method of reducing TNF.alpha. levels Emerging Cross-Sectional Technologies 136 Expired
US5874448A Substituted 2-(2,6 dioxo-3-fluoropiperidin-3-yl)-isoindolines and method of reducing TNF.alpha. levels Chemistry; Metallurgy 136 Expired
US6555554B2 Isoindolines, method of use, and pharmaceutical compositions Emerging Cross-Sectional Technologies 133 Expired
US6403613B1 1-oxo-and 1,3-dioxoisoindolines Emerging Cross-Sectional Technologies 131 Expired
US6395754B1 Substituted 2-(2,6-dioxopiperidin-3-yl)- phthalimides and 1-oxoisoindolines and method of reducing TNF&agr; levels Emerging Cross-Sectional Technologies 131 Expired
US6380239B1 Substituted 1-oxo- and 1,3-dioxoisoindoline and method of reducing inflammatory cytokine levels Human Necessities 125 Expired
US5728844A Immunotherapeutic agents Chemistry; Metallurgy 107 Expired
US7244759B2 Isoindoline compounds and methods of making and using the same Chemistry; Metallurgy 93 Expired
US7091353B2 Isoindole-imide compounds, compositions, and uses thereof Chemistry; Metallurgy 85 Expired
US6011050A Substituted phenethylsulfones and method of reducing TNF.alpha. levels Emerging Cross-Sectional Technologies 80 Expired
US5605914A Imides Chemistry; Metallurgy 66 Expired
US6326388A Substituted 1,3,4-oxadiazoles and a method of reducing TNF-alpha level Emerging Cross-Sectional Technologies 65 Expired
US5801195A Immunotherapeutic aryl amides Emerging Cross-Sectional Technologies 61 Expired
US5658940A Succinimide and maleimide cytokine inhibitors Chemistry; Metallurgy 61 Expired

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.