Prodrugs for the therapy of tumors and inflammatory disorders

US5935995A · kind A · utility

Assignee

• Heochst Aktiengesellschaft · DE

Inventors

• Klaus Bosslet · Marburg, DE
• Jorg Czech · Marburg, DE
• Manfred Gerken · Marburg, DE
• Rainer Straub · Marburg, DE
• Claude Monneret · Paris, FR
• Jean-Claude Florent · Boulogne-Billancourt, FR
• Frederic Schmidt · Saint-Mandé, FR

Key dates

• Filing date: Mar 11, 1997
• Grant date: Aug 10, 1999
• Expiry date: Mar 11, 2017

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula I EQU glycosyl-Y--C(.dbd.Y)--X--!.sub.p --W(R).sub.n --Z--C(.dbd.Y)-active compound (I) are described which are suitable for the treatment of carcinomatous diseases, autoimmune diseases and chronic inflammatory diseases such as rheumatoid arthritis.