Inventor · Marburg, DE

Klaus Bosslet

44Patents
16h-index
53Co-inventors
80Inventor score

Filing activity: May 27, 1994 → Feb 7, 2008

Most-cited inventions

PatentTitleAreaCited byStatus
US5591828A Bispecific and oligospecific mono-and oligovalent receptors, the preparation and use thereof Human Necessities 411 Expired
US5959083A Tetravalent bispecific receptors, the preparation and use thereof Emerging Cross-Sectional Technologies 168 Expired
US5830880A Gene therapy of tumors with an endothelial cell-specific, cell cycle-dependent active compound Chemistry; Metallurgy 146 Expired
US5621002A Prodrugs for enzyme mediated activation Performing Operations; Transporting 103 Expired
US5561119A Glycosylated prodrugs, their method of preparation and their uses Chemistry; Metallurgy 61 Expired
US5955100A Prodrugs their preparation and use as pharmaceuticals Emerging Cross-Sectional Technologies 51 Expired
US7129254B2 Effector conjugates, process for their production and their pharmaceutical use Chemistry; Metallurgy 41 Expired
US6241961A Radioimmuno conjugates for use in human therapy and method for their preparation Performing Operations; Transporting 28 Expired
US6146658A Prodrugs, their preparation and use as pharmaceuticals Emerging Cross-Sectional Technologies 28 Expired
US5935995A Prodrugs for the therapy of tumors and inflammatory disorders Human Necessities 26 Expired
US5877158A Pro-prodrugs, their production and use Performing Operations; Transporting 25 Expired
US7060495B2 Fusion proteins for prodrug activation Chemistry; Metallurgy 23 Expired
US6548067B1 Antigenic constructs of major histocompatibility complex class I antigens with specific carrier molecules, the preparation and use thereof Chemistry; Metallurgy 23 Expired
US6020315A Preparation having increased in vivo tolerability Human Necessities 20 Expired
US5710134A Combination of necrosis-inducing substances with substances which are activated by necroses for the selective therapy of tumors and inflammatory disorders Human Necessities 19 Expired
US6602688B1 Cytoplasmic expression of antibodies, antibody fragments and antibody fragment fusion proteins in E. coli Emerging Cross-Sectional Technologies 18 Expired
US6926896B2 Monoclonal antibodies (MAbs) against tumor-associated antigens, the preparation and use thereof Chemistry; Metallurgy 13 Expired
US6294172A Monoclonal antibodies with specificity for membrane-associated antigens Human Necessities 11 Expired
US6008023A Cytoplasmic expression of antibodies, antibody fragments and antibody fragment fusion proteins in E. coli Emerging Cross-Sectional Technologies 10 Expired
US6610299B1 Glycosyl-etoposide prodrugs, a process for preparation thereof and the use thereof in combination with functionalized tumor-specific enzyme conjugates Chemistry; Metallurgy 9 Expired
US5643731A Use of pairs of leucine zipper peptides in immunoassay methods Emerging Cross-Sectional Technologies 6 Expired
US5639622A Monoclonal antibodies against tumor-associated antigens, a process for the preparation thereof and the use thereof Human Necessities 5 Expired
US5686583A Specific antibodies against activated platelets, the preparation thereof and the use thereof in diagnosis and therapy Chemistry; Metallurgy 5 Expired
US5639621A Monoclonal antibodies against tumor-associated antigens Chemistry; Metallurgy 4 Expired
US5645817A Granulocyte-binding antibody constructs, their preparation and use Chemistry; Metallurgy 4 Expired

Source: USPTO / EPO open patent data. Inventor disambiguation is heuristic; counts are objective bibliographic measures.