Patent · US Expired

Use of non-peptide bradykinin antagonists for the treatment or prevention of Alzheimer's disease

US5952346A · kind A · utility

10Cited by

4References

5Claims

0Family size

Assignee

Hoechst Marion Roussel Deutschland GmbH · DE

Inventors

Holger Heitsch · Hofheim, DE
Klaus Wirth · Frankfurt am Main, DE
Gabriele Wiemer · Kronberg, DE

Key dates

Filing date	Oct 14, 1997
Grant date	Sep 14, 1999
Priority date	—
Expiry date	Oct 14, 2017

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/28
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to the use of non-peptide bradykinin antagonists for the production of pharmaceuticals for the prevention and treatment of Alzheimer's disease. Suitable Compounds are non-peptide bradykinin antagonists which inhibit the actions of the Alzheimer's protein amyloid (.beta./A4) in isolated endothelial cells, such as for example, fused heterobicyclic fluoroalkyl derivatives.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.