Protecting group for synthesizing oligonucleotide analogs
US5959099A · kind A · utility
13Cited by
44References
22Claims
0Family size
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Key dates
| Filing date | Jun 24, 1998 |
| Grant date | Sep 28, 1999 |
| Priority date | — |
| Expiry date | Jun 24, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A 2-N-amidoethyl protected nucleoside analog phosphoramidite of formula (1): ##STR1## is useful in the synthesis of a wide variety of oligonucleotide analogs. Coupling yields with phosphoramidite (1) in solution or solid phase oligonucleotide analog synthesis are high and the 2-N-amidoethyl protecting group can be removed easily under standard conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.