Spiro-substituted azacycles as modulators of chemokine receptor activity
US5962462A · kind A · utility
37Cited by
3References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 12, 1997 |
| Grant date | Oct 5, 1999 |
| Priority date | — |
| Expiry date | Dec 12, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to spiro-substituted azacycles of the Formula 1: ##STR1## (wherein R.sub.1, l, m, Q, W, X, Y, and Z are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-1, CCR-2, CCR-2A, CCR-2B, CCR-3, CCR-4, CCR-5, CXCR-3, and/or CXCR-4.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.